Need for Clinical Research
Clinical research plays a pivotal role in advancing medical knowledge, improving patient care, and driving healthcare innovation. In Pakistan, home to a diverse population and a significant burden of disease, the need for robust clinical research has never been greater. With a wide range of healthcare challenges and a rapidly evolving medical landscape, clinical research is essential for addressing local health disparities, developing context-specific therapies, and contributing to the global body of scientific evidence. By bridging the gap between research and clinical practice, clinical research has the power to transform healthcare delivery and improve health outcomes for communities across Pakistan.
Facilities
Interventional Radiology
Dedicated clinical research spaces within the hospital.
Assisted Reproductive Technology
Fully equipped patient care and monitoring areas
Medicine
Secure pharmacy with controlled storage for investigational products
Temperature-controlled investigational product storage and dispensing systems
Advanced laboratories for sample processing and analysis
Data management and monitoring systems compliant with international standards
Archiving and documentation facilities to ensure regulatory compliance
Rooms for site initiation, monitoring, and training sessions
IT-enabled workstations for trial coordination and communication
Access to hospital diagnostic and imaging services to support trial requirements
Departments
Creek General Hospital is a 500-bed multi-specialty facility offering comprehensive
healthcare services across the following departments:
• Medicine
• Surgery
• Obstetrics & Gynecology
• Orthopedics
• Pediatrics
• ENT
• Ophthalmology
• Cardiology
• Gastroenterology
• Neurology
• Nephrology
• Psychiatry
• Urology
• Pulmonology
• Infectious Disease
• Hepatology
• Oncology
• Interventional Radiology
• Neurosurgery
• Assisted Reproductive Technology
Our Team
At CTU, our greatest strength lies in our people. Meet the passionate professionals who drive our mission forward every day.
Message from the Director
The Clinical Trials Unit at Creek General Hospital (CTU-CGH) is mandated to serve as a center of excellence dedicated to advancing clinical research in Pakistan. We are committed to establishing robust systems and processes that enable the conduct of high-quality clinical trials tailored to the needs of the local population. Through these efforts, we aim to improve access to essential medicines and support healthcare providers, thereby positively influencing health outcomes and clinical practices at both national and international levels.
CTU-CGH is devoted to leading and participating in a wide range of studies that contribute to medical innovation while delivering meaningful improvements in patient care. We welcome prospective collaborators, sponsors, and participants to engage with our ongoing trials and research initiatives and to connect with us for opportunities to work together in advancing healthcare.
Thank you for your interest in the Clinical Trials Unit at Creek General Hospital. We look forward to building strong collaborations that contribute to a healthier future for communities across Pakistan and beyond.
About Us
The Clinical Trials Unit at Creek General Hospital (CTU-CGH) is registered with the Drug Regulatory Authority of Pakistan (DRAP) and is recognized for its expertise in the development and delivery of clinical trials and high-quality clinical research projects. The unit specializes in the design, conduct, and analysis of national and international multicentre trials, with staff contributing specialist disease knowledge and methodological expertise at every stage of the trial lifecycle.
All activities are conducted in strict accordance with the principles of ICH-GCP and in full compliance with applicable regulatory and ethical requirements. The Clinical Trials Unit is located within the hospital building and functions as a dedicated department that integrates clinical expertise with comprehensive trial management capabilities across the hospital and its affiliated colleges.
In addition, CTU-CGH collaborates with members of designated Academic Health Science Networks, leading national clinical and scientific experts, other Clinical Trials Units, and industry partners to advance research and innovation.
Services
Protocols Development
Contract Management
Ethics Submissions
Site
Monitoring
Protocol development and scientific writing
Contract development and management, including agreements with sponsors and CROs
Preparation and submission of ethics applications, amendments, and annual progress reports
Organization and conduct of site initiation meetings and monitoring visits
File Management
Safety Monitoring
Budget Management
Stakeholder Liaison
Preparation and maintenance of Trial Master Files, site files, and pharmacy files
Ongoing safety monitoring and protocol compliance in accordance with local and international guidelines
Financial oversight, including budget management and expense monitoring
Liaison with investigators, regulators, and sponsors for timely reporting and invoicing
Study
Closeout
Document Archiving
Product Management
Drug
Inventory
Management of study close-out activities
Archiving of study documentation as per sponsor and regulatory requirements
Investigational product management, including procurement, storage, and dispensing
Maintenance of emergency crash cart drug inventory
IP Accountability
Study Randomization
Event
Reporting
SOP Development
Maintenance of investigational product accountability logs
Generation and management of randomization lists and sealed envelopes
Adverse event reporting and management
Development and implementation of Standard Operating Procedures (SOPs)
GCP Compliance
Continuous maintenance of Good Clinical Practice (GCP) compliance throughout the trial lifecycle
Protocols Development
Protocol development and scientific writing
Contract Management
Contract development and management, including agreements with sponsors and CROs
Ethics Submissions
Preparation and submission of ethics applications, amendments, and annual progress reports
Site Monitoring
Organization and conduct of site initiation meetings and monitoring visits
File Management
Preparation and maintenance of Trial Master Files, site files, and pharmacy files
Safety Monitoring
Ongoing safety monitoring and protocol compliance in accordance with local and international guidelines
Budget Management
Financial oversight, including budget management and expense monitoring
Stakeholder Liaison
Liaison with investigators, regulators, and sponsors for timely reporting and invoicing
Study Closeout
Management of study close-out activities
Document Archiving
Archiving of study documentation as per sponsor and regulatory requirements
Product Management
Investigational product management, including procurement, storage, and dispensing
Drug Inventory
Maintenance of emergency crash cart drug inventory
IP Accountability
Maintenance of investigational product accountability logs
Study Randomization
Generation and management of randomization lists and sealed envelopes
Event Reporting
Adverse event reporting and management
SOP Development
Development and implementation of Standard Operating Procedures (SOPs)
GCP Compliance
Continuous maintenance of Good Clinical Practice (GCP) compliance throughout the trial lifecycle